A Bayesian hierarchical model for allele frequencies

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A Bayesian hierarchical model for allele frequencies.

Genetic epidemiological methodologies, such as linkage analysis, often require accurate estimates of allele frequencies. When studies involve multiple sub-populations with different evolutionary histories, accurate estimates can be difficult to obtain because the number of subjects per sub-population tends to be limited. Given allele counts for a collection of loci and sub-populations, we propo...

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ژورنال

عنوان ژورنال: Genetic Epidemiology

سال: 2000

ISSN: 0741-0395,1098-2272

DOI: 10.1002/1098-2272(200101)20:1<17::aid-gepi3>3.0.co;2-q